Phytochemical Screening, In vitro Antioxidant, Antibacterial Activities on Skimmia laureola Leaves Extract: A Research

Panshul Sharma *

IEC School of Pharmacy, IEC University, Himachal Pradesh, 174103, India.

Hans Raj

IEC School of Pharmacy, IEC University, Himachal Pradesh, 174103, India.

Diksha Choudhary

Chitkara College of Pharmacy, Chitkara University, Punjab, India-140401, India.

Pooja Kumari

Institute of Pharmaceutical Sciences, Bhaddal, Ropar, Punjab, India.

Rajdeep Kaur

IEC School of Pharmacy, IEC University, Himachal Pradesh, 174103, India.

Ankita

IEC School of Pharmacy, IEC University, Himachal Pradesh, 174103, India.

Surendar Kumar

Dreamz College of Pharmacy, Meramasit, Sundar Nagar, Himachal Pradesh, 175036, India.

*Author to whom correspondence should be addressed.


Abstract

Background: Skimmia laureola owned by the Rutaceae family is one of the plants that might use the Indian traditional treatment system in the Indian subcontinent and act against many diseases. So, this new research was carried out to scientifically confirm the various solvent fractions and separate the active fraction from the plant against antioxidants and bacterial and microbial growth.

Objectives: The main objective of the study involves the Phytochemical screening and research of invitro activities i.e. antioxidant and antibacterial from the extracts of the leaves part of the Skimmia laureola plant.

Methods: Phytochemical screening was carried out of various extracts by the tests that involved it. Invitro antibacterial and antioxidant activities were examined of the plant extract through various methods DPPH, Metal chelating activity, Reducing power ability, Hydrogen peroxide scavenging activity, and Nitric oxide scavenging activity. After completion of the research, all the activity is shown graphically.

Results: Invitro antioxidant activity shows that methanolic extract shows more antioxidant activity than other extracts. The antibacterial investigations show that the ethanolic extract of the plant removal was very compelling for bacterias Streptococcus aureus, Bacillus subtilis, and Escherichia coli at 25 μg/ml, 50 μg/ml, 75 μg/ml, 100 μg/ml, 200 μg/ml and 300 μg/ml individually.

Conclusion: Auxiliary metabolites (phenol, flavonoid, tannin, and content) have been quantified. In antioxidant tests such as DPPH activity, the methanolic extract of the plant outperforms other extracts such as chloroform, petroleum ether, ethanol, and aqueous extract. The antibacterial investigations show that the ethanolic extract of the plant removed was very compelling for bacterias Streptococcus aureus, Bacillus subtilis, and E.coli. The current study may be useful in improving data regarding its distinguishing proof boundaries expected primarily in the method of the adequacy of homegrown medications in the current situation lacking administrative laws to control the nature of natural medications, as well as discovering antioxidants and antibacterial action.

Keywords: Pharmacognostical, medications, Skimmia laureola, antioxidants


How to Cite

Sharma , Panshul, Hans Raj, Diksha Choudhary, Pooja Kumari, Rajdeep Kaur, Ankita, and Surendar Kumar. 2023. “Phytochemical Screening, In Vitro Antioxidant, Antibacterial Activities on Skimmia Laureola Leaves Extract: A Research”. European Journal of Medicinal Plants 34 (11):40-55. https://doi.org/10.9734/ejmp/2023/v34i111169.