European Journal of Medicinal Plants http://journalejmp.com/index.php/EJMP <p style="text-align: justify;"><strong>European Journal of Medicinal Plants (ISSN: 2231-0894)</strong> is dedicated to publish&nbsp;high quality papers (<a href="/index.php/EJMP/general-guideline-for-authors">Click here for Types of paper</a>)&nbsp;in all areas of medicinal plants research including plant growth and development, agronomic management, plant nutrition, plant physiology, cell biology, molecular biology, biotechnology, medicinal properties, phytochemical constituents, fitoterapia, pharmacognosy, essential oils, ehnopharmacology and phytomedicine. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer reviewed, open access INTERNATIONAL journal.</p> en-US contact@journalejmp.com (European Journal of Medicinal Plants) contact@journalejmp.com (European Journal of Medicinal Plants) Fri, 20 Mar 2020 13:04:47 +0000 OJS 3.1.1.4 http://blogs.law.harvard.edu/tech/rss 60 In silico Analysis of Phytochemicals from Cocoa against Ribitol-5-Phosphate 2-Dehydrogenase of Streptococcus pneumoniae Causing Pneumonia http://journalejmp.com/index.php/EJMP/article/view/30240 <p>This analysis aims at evaluating the effects of Cocoa extract on Pneumonia. Pneumonia is caused by <em>Streptococcus pneumoniae</em>. Caffeine, Chorogenic acid, Ferulic acid, Iso- Orientin, luteolin, Naringenin and Vanillic acid of Cocoa were interacted with ribitol-5-phosphate 2-dehydrogenase which is involved in pentose and glucorunate interconversion pathways of <em>Streptococcus pneumoniae</em>. The enzyme was taken as receptor and phytochemicals were considered as ligands. All the interactions were done in Biovia discovery Studio 2020 and the process is known as molecular Docking. Molecular Docking provides us an opportunity to identify the potential phytochemical or component which can act as powerful tool against the pathogen. Out of all the phytochemicals, Luteolin of Cocoa inhibits or blocks the mechanism or action of ribitol-5-phosphate 2-dehydrogenase enzyme of <em>Streptococcus pneumoniae.</em> There is high possibility that these phytochemicals can potentially inhibit others enzymes involved in various metabolic pathways of <em>Streptococcus pneumoniae</em>.</p> Sunanya Das, Suchismita Khatei, Saismita Sahoo, Sitaram Swain, Dipankar Bhattacharyay ##submission.copyrightStatement## http://journalejmp.com/index.php/EJMP/article/view/30240 Fri, 20 Mar 2020 00:00:00 +0000