European Journal of Medicinal Plants <p style="text-align: justify;"><strong>European Journal of Medicinal Plants (ISSN: 2231-0894)</strong> is dedicated to publish&nbsp;high quality papers (<a href="/index.php/EJMP/general-guideline-for-authors">Click here for Types of paper</a>)&nbsp;in all areas of medicinal plants research including plant growth and development, agronomic management, plant nutrition, plant physiology, cell biology, molecular biology, biotechnology, medicinal properties, phytochemical constituents, fitoterapia, pharmacognosy, essential oils, ehnopharmacology and phytomedicine. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer reviewed, open access INTERNATIONAL journal.</p> SCIENCEDOMAIN international en-US European Journal of Medicinal Plants 2231-0894 Attitudes, Knowledge and Practice of Herbal Remedy Use among the Population Visiting Pharmacies and Health Care Providers in Alexandria, Egypt: A Cross-Sectional Study <p><strong>Aims: </strong>To show the levels of awareness, attitude, practices and socioeconomic factors related to consuming herbal products among Alexandrian citizen visiting pharmacies. The findings of this study are meant also to show the practices and beliefs of healthcare providers regarding using herbal remedies in treatment, including advising patients, reporting adverse effects and possessing knowledge about specific herb-drug interactions.</p> <p><strong>Study Design:</strong>&nbsp; people visiting pharmacies as well as pharmacists in their pharmacies and physicians in their clinics were invited to complete a questionnaire about their knowledge and personal experience in the consumption of herbal remedy. Anonymity was guaranteed. Questionnaire consists of three parts: demographic data, personal experience and a part concerning health care providers.</p> <p><strong>Place and Duration of Study: </strong>Study area is the city of Alexandria, Egypt from the 1<sup>st</sup> July through September 2018.</p> <p><strong>Methodology: </strong>This is a descriptive cross-sectional study that used a self-administered, questionnaire from 213 participants (153+ 60 health care providers HCPs).</p> <p><strong>Results: </strong>Almost half the respondents preferred to be treated with herbs because they believed that herbs are safe. But they are not the proper choice to cure chronic diseases. Only 25% of herb users recorded suffering from side effects. The most common source of information about herbs was via internet, followed by family and friends, television and other types of media. Herbal remedies were purchased mainly from outlets other than pharmacies. The willingness to buy such products was not affected by participants’ education level or their monthly income. The public didn’t feel it’s important to mention any herbal remedy they consume to their physician; similarly HCPs did not ask them. Generally, it was shown that HCPs have inadequate knowledge about herbs.</p> <p><strong>Conclusion: </strong>The prevalence of herb usage is moderate among the Alexandrian population. And it is imperative to educate HCPs about the benefits, risks and interactions of herbal supplements.</p> Hoda Fathy Raghda El-Hawy Raghda Hassan ##submission.copyrightStatement## 2019-11-15 2019-11-15 1 10 10.9734/ejmp/2019/v30i230170 Green Combustion Synthesis of CeO2 and TiO2 Nanoparticles Doped with Same Oxide Materials of ZrO2: Investigation of in vitro Assay with Antibiotic Resistant Bacterium (ARB) and Anticancer Effect <p>This article reports the synthesis, characteristics and biomedical applications of CeO<sub>2</sub>-ZrO<sub>2</sub> and TiO<sub>2</sub>-ZrO<sub>2</sub> nanoparticles. The nanoparticles are synthesized by Green combustion method. Aloe Vera, dates and pomegranate extracts are used as mediators to avoid toxicity instead of chemical reagents. Hence it is biocompatible, non-toxic and avoiding adverse effect in biomedical applications. The nanoparticles are characterized by XRD to confirm the physical structure. The FTIR, Raman and SEM with EDAX analyses the chemical composition and their morphology. The antibacterial activity of these nanoparticles is assayed by well diffusion method against the bacterial pathogens of <em>Stephylococcusaureus, Shigillaflexneri</em> and <em>Bacillus sp</em>. The anticancer effect of the nanoparticles is investigated on A549 cell line by <em>In Vitro</em> assay. The conceivable purpose is the hydroxyl radicals which are easily produced by oxidizing more hydroxide ions in alkaline solution. Thus the competence of the development is rationally improved at pH is 9.</p> A. Mohamed Saleem S. Rajasekar K. Kaviyarasu R. Perumalsamy A. Ayeshamariam M. Jayachandran ##submission.copyrightStatement## 2019-11-19 2019-11-19 1 17 10.9734/ejmp/2019/v30i230171 Antioxidant and Anticonvulsant Effect of Dennettia Tripetala on Rat Model of Isoniazid-induced Seizure <p><strong>Aims: </strong>This study aimed at investigating the antioxidative, anticonvulsive and histological effects of ethanolic fruit extract of <em>Dennettia tripetala</em> on the pre-frontal lobe of the brain in isoniazid-induced (300 mg/kg, i.p) seizure in adult wistar rat.</p> <p><strong>Introduction:</strong> Neuronal hyper-excitability and excessive production of free radicals have been implicated in the pathogenesis of a considerable range of neurological disorders, including epilepsy. The high rate of oxidative metabolism, coupled with the low antioxidant defenses and the richness in polyunsaturated fatty acids, makes the brain highly vulnerable to free radical damage.</p> <p><strong>Study Design:</strong>&nbsp;This is an original research conducted in Department of Anatomy, Faculty of Basic Medical Sciences, Enugu State University of Science and Technology (ESUT), Parklane, Enugu State, Nigeria, between June and August, 2019.</p> <p><strong>Methodology:&nbsp;</strong>A total number of twenty four wistar rats were used for this experiment, the animals were grouped into six groups with four animals per group, Group I served as the negative control, Group II served as the positive control, Group III received the standard drug as well as the Isoniazid, while group IV,&nbsp; V and VI&nbsp; were treated with&nbsp; ethanolic extract of <em>Dennettia tripetala </em>at different dosages; 250 mg/kg, 500 mg/kg and 750 mg/kg, intraperitoneally (i.p) respectively and its effects compared with a standard drug (Pyridoxine) treated group.</p> <p><strong>Results: </strong>The extract significantly prolonged the onset of seizure at high dose administration (750 mg/kg) but completely prevented seizure occurrence at low and medium dose administration (250 mg/kg and 500 mg/kg, i.p) when induced with isoniazid (300 mg/kg, i.p.).</p> <p><strong>Conclusion:</strong> The results obtained from this work suggest that ethanolic extract of <em>Dennettia tripetala</em> has anticonvulsant activity, and this supports the use of the formulation traditionally in the treatment of convulsions, thus should be considered for clinical trials.</p> Elizabeth Finbarrs-Bello Ignatius Ikemefuna Ozor Samsudeen G. Ojuolape Abonyi Ernest Obinna ##submission.copyrightStatement## 2019-11-21 2019-11-21 1 10 10.9734/ejmp/2019/v30i230172