http://journalejmp.com/index.php/EJMP/issue/feed European Journal of Medicinal Plants 2020-02-22T10:40:12+00:00 European Journal of Medicinal Plants contact@journalejmp.com Open Journal Systems <p style="text-align: justify;"><strong>European Journal of Medicinal Plants (ISSN: 2231-0894)</strong> is dedicated to publish&nbsp;high quality papers (<a href="/index.php/EJMP/general-guideline-for-authors">Click here for Types of paper</a>)&nbsp;in all areas of medicinal plants research including plant growth and development, agronomic management, plant nutrition, plant physiology, cell biology, molecular biology, biotechnology, medicinal properties, phytochemical constituents, fitoterapia, pharmacognosy, essential oils, ehnopharmacology and phytomedicine. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer reviewed, open access INTERNATIONAL journal.</p> http://journalejmp.com/index.php/EJMP/article/view/30210 Anticancer Activity of Silver Nanoparticle by Using Cassia auriculata Extract 2020-02-22T06:29:42+00:00 M. Prem Nawaz A. Afroos Banu S. Raja Mohamed M. Palanivelu A. Ayeshamariam aamariam786@gmail.com <p>In this study, green synthesis of silver nanoparticles (Ag NPs) has done using traditional herbal namely <em>Cassia auriculata</em> extract by the simple Green synthesis method. The synthesized Ag nanoparticles were studied by the characterization techniques includes X-ray diffraction (XRD) crystallography for nature of crystalline with relevant parameters, Transmission electron microscopy (TEM) for particle size as well as the SAED patterns for amorphous, crystalline or polynanocrystalline and Photoluminescence analysis were carried out for the prepared NPs. Ag NPs were fabricated utilizing Phyto-aquatic extract of <em>Cassia auriculata</em> which act as a reducing agent, and it was converted into a precursor solution to coat on cotton fabrics for antibacterial applications. To further, its performance on anticancer application was studied for Michigan Cancer Foundation-7 (MCF-7) line breast cancer.</p> 2020-02-22T00:00:00+00:00 ##submission.copyrightStatement## http://journalejmp.com/index.php/EJMP/article/view/30211 Evaluation of Antioxidant and Anti-Parkinson Activity of Portulaca oleracea Seed Methanolic Extract 2020-02-22T10:40:12+00:00 Santosh Kumar Vaidya skvaidya1979@gmail.com Dharmesh K. Golwala Darpini S. Patel Satyajit Sahoo <p><strong>Aim:</strong> Evaluation of Antioxidant and Anti-Parkinson activity of <em>Portulaca oleracea</em> seed methanolic extract.</p> <p><strong>Place:</strong> C. U. Shah College of Pharmacy and Research, Wadhwan, Surendranagar, Gujarat, India.</p> <p><strong>Methodology: </strong>Collect plant materials were extracted with methanol. Extract was subjected to qualitative and quantitative investigation and antioxidant properties of extract was determine by Nitric oxide free radical scavenging activity and Reducing power by FeCl<sub>3</sub> method.</p> <p>Anti-Parkinson activity evaluated by two behavioral models namely, haloperidol induced catalepsy, and orofacial dyskinesia both models various behavioral activity/ parameter (catalepsy, vacuous chewing movement and tongue protrusion) were evaluated.</p> <p><strong>Results: </strong>Preliminary qualitative phytochemical screening was to reveal presence of polyphenols, flavanoids, glycoside, alkaloids, carbohydrates and reducing sugar etc. Based preliminary qualitative phytochemical screening; quantitative estimation of methanolic extract showed significant amount of polyphenols. <em>In-vitro</em> antioxidants was performed by two method reducing power by FeCl<sub>3</sub> and nitric oxide free radical scavenging, the methanolic extract shows significant antioxidant properties, based on polyphenols and antioxidant properties extracts was used for the Anti-Parkinson activity Haloperidol induced catalepsy in mice Treatment with <em>Portulaca oleracea</em> seed showed a significant (P&lt;0.01) reduction in the duration of cataleptic behavior dose dependently when compared to haloperidol treated group. Haloperidol induced orofacial dyskinesia in rat recovery of orofacial dyskinesia as evidenced by decrease in the frequency of vacuous chewing movement and tongue significant (P&lt;0.05) decrease in the frequency of vacuous chewing &amp; tongue protrusion while <em>Portulaca oleracea</em> seed (200 mg/kg) was found to be insignificant in this respect.</p> <p><strong>Conclusion: </strong>After <em>Portulaca oleracea </em>seed (MLPO) treatment, the significant alterations produced in Parkinson’s affected rodents in respect to lipid peroxidation and antioxidant concentration significantly contributing its antioxidant potential. This antiperoxide action observed in <em>Portulaca oleracea </em>seed (MLPO) treated animals might be due to the suppression of the production of reactive oxygen species. This compound may be found to scavenge free radicals, including hydroxyl anions and reduce the level of lipid peroxidation in MLPO animals. Inhibition of oxidative stress may be one of the possible mechanisms for the anti-Parkinson effects of <em>Portulaca oleracea </em>seed (MLPO).</p> 2020-02-22T00:00:00+00:00 ##submission.copyrightStatement##