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Physalis angulata Linn. and Physalis micrantha Linn. (Solanaceae) used for different medicinal purposes in Nigeria and other parts of the world were subjected to high performance liquid chromatography (HPLC) analysis to determine their phytochemical profiles. Forty five (45) alkaloids, 36 flavonoids, 18 glycosides and 44 phenolic acids were observed in the plants. P. angulata had the highest concentrations of flavonoids, phenolic acids and alkaloids while P. micarantha had the highest concentration of glycosides. The presence and concentration of these chemicals in these studied species confirm their medicinal and ethno-botanical uses and make them potential sources of raw materials for the pharmaceutical industries.
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